Structure of PDB 1yzt Chain B Binding Site BS01

Receptor Information
>1yzt Chain B (length=154) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGK
RVNLAIWDTARDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCI
VGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKR
MIET
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1yzt Chain B Residue 800 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1yzt Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		T33 T51
Binding residue
(residue number reindexed from 1)		T17 T35
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0032482 Rab protein signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:1yzt, PDBe:1yzt, PDBj:1yzt
PDBsum1yzt
PubMed16034420
UniProtQ9UL25|RAB21_HUMAN Ras-related protein Rab-21 (Gene Name=RAB21)

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