Structure of PDB 1ytv Chain B Binding Site BS01

Receptor Information

>1ytv Chain B (length=366) Species: 562 (Escherichia coli)

KIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQV
AATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYN
GKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFN
LQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIK
NKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLG
AVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINA
ASGRQTVDEALKDAQT

Ligand information

>1ytv Chain N (length=5) Species: 9606 (Homo sapiens)

NSSSN

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1ytv A C-terminal segment of the V1R vasopressin receptor is unstructured in the crystal structure of its chimera with the maltose-binding protein.
• Resolution: 1.8 Å
• Binding residue (original residue number in PDB): I192 A352 D377 A378 T380
• Binding residue (residue number reindexed from 1): I178 A338 D363 A364 T366

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0015144 carbohydrate transmembrane transporter activity
• GO:1901982 maltose binding

Biological Process

• GO:0006974 DNA damage response
• GO:0008643 carbohydrate transport
• GO:0015768 maltose transport
• GO:0034219 carbohydrate transmembrane transport
• GO:0034289 detection of maltose stimulus
• GO:0042956 maltodextrin transmembrane transport
• GO:0055085 transmembrane transport
• GO:0060326 cell chemotaxis

Cellular Component

• GO:0016020 membrane
• GO:0030288 outer membrane-bounded periplasmic space
• GO:0042597 periplasmic space
• GO:0043190 ATP-binding cassette (ABC) transporter complex
• GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
• GO:1990060 maltose transport complex

External links

• PDB: RCSB:1ytv, PDBe:1ytv, PDBj:1ytv
• PDBsum: 1ytv
• PubMed: 16511036
• UniProt: P0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE)