Structure of PDB 1ytu Chain B Binding Site BS01

Receptor Information
>1ytu Chain B (length=427) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMEYKIVENGLTYRIGNGASVPISNTGELIKGLRNYGPYEVPSLKYNQIA
LIHNNQFSSLINQLKSQISSKIDEVWHIHNINISEFIYDSPHFDSIKSQV
DNAIDTGVDGIMLVLPEYNTPLYYKLKSYLINSIPSQFMRYDILSNRNLT
FYVDNLLVQFVSKLGGKPWILNVDPEKGSDIIIGTGATRIDNVNLFCFAM
VFKKDGTMLWNEISPIVTSSEYLTYLKSTIKKVVYGFKKSNPDWDVEKLT
LHVSGKRPKMKDGETKILKETVEELKKQEMVSRDVKYAILHLNETHPFWV
MGDPNNRFHPYEGTKVKLSSKRYLLTLLQPYLKRNGLEMVTPIKPLSVEI
VSDNWTSEEYYHNVHEILDEIYYLSKMNWRGFRSRNLPVTVNYPKLVAGI
IANVNRYGGYPINPEGNRSLQTNPWFL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ytu Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Y118 N119 T120 Y123 K127 Q137 F138 M139 R140 I143 R147 Y152 N155 Q159 K163 R380 R385 L427
Binding residue
(residue number reindexed from 1)		Y118 N119 T120 Y123 K127 Q137 F138 M139 R140 I143 R147 Y152 N155 Q159 K163 R380 R385 L427
Binding affinityPDBbind-CN: Kd=0.19uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1ytu, PDBe:1ytu, PDBj:1ytu
PDBsum1ytu
PubMed15800629
UniProtO28951|PIWI_ARCFU Piwi protein (Gene Name=AF_1318)

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