Structure of PDB 1yk1 Chain B Binding Site BS01

Receptor Information
>1yk1 Chain B (length=394) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGLLPPGTRFQVA
YEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDL
PMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAAL
VYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ
ASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSW
KRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMED
YVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAG
QVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRP
Ligand information
>1yk1 Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GCFGRKMDRISSSSGLGCKVL
Receptor-Ligand Complex Structure
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PDB1yk1 Structural determinants of natriuretic peptide receptor specificity and degeneracy.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		Y93 R100 G118 K163 Y169 E173 E177 Y189 S190 D192
Binding residue
(residue number reindexed from 1)		Y86 R93 G111 K156 Y162 E166 E170 Y182 S183 D185
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1yk1, PDBe:1yk1, PDBj:1yk1
PDBsum1yk1
PubMed16870210
UniProtP17342|ANPRC_HUMAN Atrial natriuretic peptide receptor 3 (Gene Name=NPR3)

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