Structure of PDB 1yk0 Chain B Binding Site BS01

Receptor Information
>1yk0 Chain B (length=394) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGLLPPGTRFQVA
YEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDL
PMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAAL
VYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ
ASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSW
KRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMED
YVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAG
QVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRP
Ligand information
>1yk0 Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SCFGGRMDRIGAQSGLGCNSF
Receptor-Ligand Complex Structure
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PDB1yk0 Structural determinants of natriuretic peptide receptor specificity and degeneracy.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		N65 Y93 R100 G118 F119 Y159 D161 K163 Y169 E173 Y189 S190 F191
Binding residue
(residue number reindexed from 1)		N58 Y86 R93 G111 F112 Y152 D154 K156 Y162 E166 Y182 S183 F184
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1yk0, PDBe:1yk0, PDBj:1yk0
PDBsum1yk0
PubMed16870210
UniProtP17342|ANPRC_HUMAN Atrial natriuretic peptide receptor 3 (Gene Name=NPR3)

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