Structure of PDB 1xv2 Chain B Binding Site BS01

Receptor Information
>1xv2 Chain B (length=232) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVLYQHGTLGTLMAGLLEGTATINELLEHGNLGIATLTGSDGEVIFLDGK
AYHANEHKEFIELKGDEKVPYASITNFKASKTFPLQQLSQDDVFAQIKNE
MLSENLFSAVKIYGTFKHMHVRMMPAQQPPYTRLIDSARRQPEEKRQDIR
GAIVGFFTPELFHGVGSAGFHIHFADDERAYGGHVLDFEVDDVVVEIQNF
ETFQQHFPVNNETFVKAKIDYKDVAEEIREAE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1xv2 Chain B Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1xv2 Crystal structure of a hypothetical protein similar to alpha-acetolactate
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H173 H175 H186
Binding residue
(residue number reindexed from 1)		H171 H173 H184
Annotation score1
Enzymatic activity
Enzyme Commision number 4.1.1.5: acetolactate decarboxylase.
Gene Ontology
Molecular Function
GO:0016831 carboxy-lyase activity
GO:0046872 metal ion binding
GO:0047605 acetolactate decarboxylase activity
Biological Process
GO:0045151 acetoin biosynthetic process

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:1xv2, PDBe:1xv2, PDBj:1xv2
PDBsum1xv2
PubMed
UniProtA0A0H3JS15

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