Structure of PDB 1xdk Chain B Binding Site BS01

Receptor Information

>1xdk Chain B (length=245) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSEL
ATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQ
DTMTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSA
ICLICGDRQDLEEPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKI
TDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGHEPLTPS

Ligand information

>1xdk Chain D (length=10) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

HPMLMNLLKD

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1xdk CHARACTERIZATION OF THE INTERACTION BETWEEN RAR/RXR HETERODIMERS AND TRANSCRIPTIONAL COACTIVATORS THROUGH STRUCTURAL AND FLUORESCENCE ANISOTROPY STUDIES
Resolution	2.9 Å
Binding residue (original residue number in PDB)	K237 Q250 I251 K255 P401 L402 E405
Binding residue (residue number reindexed from 1)	K63 Q76 I77 K81 P227 L228 E231

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004879	nuclear receptor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0048384	retinoic acid receptor signaling pathway

	Cellular Component
GO:0005634	nucleus

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Cellular Component

External links

PDB	RCSB:1xdk, PDBe:1xdk, PDBj:1xdk
PDBsum	1xdk
PubMed	15528208
UniProt	P22605\|RARB_MOUSE Retinoic acid receptor beta (Gene Name=Rarb)

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