Structure of PDB 1w0u Chain B Binding Site BS01
Receptor Information
>1w0u Chain B (length=55) Species:
9606
(Homo sapiens) [
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KKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMK
RLGMN
Ligand information
>1w0u Chain C (length=16) [
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ctagggttagggttag
Receptor-Ligand Complex Structure
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PDB
1w0u
How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
K447 G468 W470 A471 K488 R492
Binding residue
(residue number reindexed from 1)
K2 G23 W25 A26 K43 R47
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0042162
telomeric DNA binding
Biological Process
GO:0000723
telomere maintenance
GO:0031848
protection from non-homologous end joining at telomere
Cellular Component
GO:0000781
chromosome, telomeric region
GO:0005634
nucleus
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Cellular Component
External links
PDB
RCSB:1w0u
,
PDBe:1w0u
,
PDBj:1w0u
PDBsum
1w0u
PubMed
15608617
UniProt
Q15554
|TERF2_HUMAN Telomeric repeat-binding factor 2 (Gene Name=TERF2)
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