Structure of PDB 1vix Chain B Binding Site BS01

Receptor Information
>1vix Chain B (length=410) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLI
NVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENY
RGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEI
MTALAVLQQKKIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGG
GVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPAD
ESPEMTEGYEGFYHLASMKGTVERADMHYIIRDFDRKQFEARKRKMMEIA
KKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCDIEPE
LKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIV
RIAELTAQRK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1vix Chain B Residue 419 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1vix Structural analysis of a set of proteins resulting from a bacterial genomics project
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H78 D140 D196
Binding residue
(residue number reindexed from 1)		H80 D142 D198
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.11.4: tripeptide aminopeptidase.
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0042803 protein homodimerization activity
GO:0045148 tripeptide aminopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0043171 peptide catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1vix, PDBe:1vix, PDBj:1vix
PDBsum1vix
PubMed16021622
UniProtP29745|PEPT_ECOLI Peptidase T (Gene Name=pepT)

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