Structure of PDB 1v3e Chain B Binding Site BS01

Receptor Information

>1v3e Chain B (length=431) Species: 11216 (Human respirovirus 3) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCI
RTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGIITVNSDLVPDLNP
RISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASPGIEDIVLD
IVNYDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLE
HPINENVICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSI
PKLKVWTISMRQNYWGSEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITD
YSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIV
SSVILDSQKSRVNPVITYSTATERVNELAILNRTLSAGYTTTSCITHYNK
GYCFHIVEINHKSLNTLQPMLFKTEIPKSCS

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

1v3e Chain B Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1v3e Structure of the Haemagglutinin-neuraminidase from Human Parainfluenza Virus Type III
Resolution	1.89 Å
Binding residue (original residue number in PDB)	D279 S282 G284 A316
Binding residue (residue number reindexed from 1)	D138 S141 G143 A175
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.2.1.18: exo-alpha-sialidase.

Gene Ontology

	Molecular Function
GO:0004308	exo-alpha-sialidase activity
GO:0046789	host cell surface receptor binding

	Biological Process
GO:0019058	viral life cycle

	Cellular Component
GO:0019031	viral envelope

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1v3e, PDBe:1v3e, PDBj:1v3e
PDBsum	1v3e
PubMed	14729348
UniProt	Q6WJ03

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