Structure of PDB 1uhb Chain B Binding Site BS01

Receptor Information
>1uhb Chain B (length=98) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQG
DSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN
Ligand information
Receptor-Ligand Complex Structure
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PDB1uhb Trypsin activity reduced by an autocatalytically produced nonapeptide.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		Y151 D189 S190 C191 Q192 G193 S195 V213 S214 W215 G216 Y217 G219 C220 G226
Binding residue
(residue number reindexed from 1)		Y6 D46 S47 C48 Q49 G50 S52 V66 S67 W68 G69 Y70 G71 C72 G79
Enzymatic activity
Catalytic site (original residue number in PDB) Q192 G193 D194 S195 G196
Catalytic site (residue number reindexed from 1) Q49 G50 D51 S52 G53
Enzyme Commision number 3.4.21.4: trypsin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1uhb, PDBe:1uhb, PDBj:1uhb
PDBsum1uhb
PubMed15106996
UniProtP00761|TRYP_PIG Trypsin

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