Structure of PDB 1u12 Chain B Binding Site BS01

Receptor Information
>1u12 Chain B (length=127) Species: 266835 (Mesorhizobium japonicum MAFF 303099) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDFVRNWQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGD
RMFFVVEGSVSVATPNPVELGPGAFFGEMALISGEPRSATVSAATTVSLL
SLHSADFQMLCSSSPEIAEIFRKTALE
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain1u12 Chain B Residue 920 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1u12 Structural Basis of Ligand Activation in a Cyclic Nucleotide Regulated Potassium Channel
Resolution2.7 Å
Binding residue
(original residue number in PDB)		A283 P287
Binding residue
(residue number reindexed from 1)		A63 P67
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity

View graph for
Molecular Function
External links
PDB RCSB:1u12, PDBe:1u12, PDBj:1u12
PDBsum1u12
PubMed15550244
UniProtQ98GN8|CNGK1_RHILO Cyclic nucleotide-gated potassium channel mll3241 (Gene Name=mll3241)

[Back to BioLiP]