Structure of PDB 1tx3 Chain B Binding Site BS01

Receptor Information
>1tx3 Chain B (length=254) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKRPKTLSGHAAGEPFEKLVYKFLKENLSDLT
FKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIEN
LFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQTCA
KMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWA
AAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPF
KKYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1tx3 Ca2+ binding in the active site of HincII: implications for the catalytic mechanism
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H31 Q109 N110 D114 D127 T130 N132 S136 A137 Q138 P140 N141 S144 K147 A205 Q207
Binding residue
(residue number reindexed from 1)		H28 Q106 N107 D111 D124 T127 N129 S133 A134 Q135 P137 N138 S141 K144 A202 Q204
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1tx3, PDBe:1tx3, PDBj:1tx3
PDBsum1tx3
PubMed15491133
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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