Structure of PDB 1tfc Chain B Binding Site BS01
Receptor Information
>1tfc Chain B (length=225) Species:
9606
(Homo sapiens) [
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PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGW
AKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIM
DEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHI
EDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAV
QHFYNIKLEGKVPMHKLFLEMLEAK
Ligand information
>1tfc Chain D (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQE
Receptor-Ligand Complex Structure
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PDB
1tfc
Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
I280 K284 L294 M298 K448 L449 E452 M453
Binding residue
(residue number reindexed from 1)
I48 K52 L62 M66 K216 L217 E220 M221
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1tfc
,
PDBe:1tfc
,
PDBj:1tfc
PDBsum
1tfc
PubMed
15161930
UniProt
P62508
|ERR3_HUMAN Estrogen-related receptor gamma (Gene Name=ESRRG)
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