Structure of PDB 1sxt Chain B Binding Site BS01

Receptor Information

>1sxt Chain B (length=220) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KDLRKKSELQGTALGNLKQIYYYNEKAKTENKESHDQFLQHTILFKGFFT
DHSWYNDLLVDFDSKDIVDKYKGKKVDLYGAYYGYQCANKTACMYGGVTL
HDNNRLTEEKKVPINLWLDGKQNTVPLETVKTNKKNVTVQELDLQARRYL
QEKYNLYNSDVFDGKVQRGLIVFHTSTEPSVNYDLFGAQGQYSNTLLRIY
RDNKTINSENMHIDIYLYTS

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

1sxt Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	1sxt The Co-crystal structure of staphylococcal enterotoxin type A with Zn2+ at 2.7 A resolution. Implications for major histocompatibility complex class II binding.
Resolution	2.7 Å
Binding residue (original residue number in PDB)	H187 H225 D227
Binding residue (residue number reindexed from 1)	H174 H212 D214
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005515	protein binding
GO:0042289	MHC class II protein binding
GO:0046872	metal ion binding
GO:0090729	toxin activity

	Biological Process
GO:0035821	modulation of process of another organism

	Cellular Component
GO:0005576	extracellular region

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:1sxt, PDBe:1sxt, PDBj:1sxt
PDBsum	1sxt
PubMed	8943278
UniProt	P0A0L2\|ETXA_STAAU Enterotoxin type A (Gene Name=entA)

[Back to BioLiP]