Structure of PDB 1sx5 Chain B Binding Site BS01

Receptor Information
>1sx5 Chain B (length=238) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTAVLSTIFELFSRPI
INKIAEKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNEKIK
FTLGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVKSSLKTYNINELN
EIPKPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFD
SEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIYRGRK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1sx5 DNA cleavage by EcoRV endonuclease: Two metal ions in three metal ion binding sites
Resolution1.5 Å
Binding residue
(original residue number in PDB)		S183 G184 N185 S223 R226
Binding residue
(residue number reindexed from 1)		S176 G177 N178 S216 R219
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1sx5, PDBe:1sx5, PDBj:1sx5
PDBsum1sx5
PubMed15170321
UniProtP04390|T2E5_ECOLX Type II restriction enzyme EcoRV (Gene Name=ecoRVR)

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