Structure of PDB 1svl Chain B Binding Site BS01

Receptor Information
>1svl Chain B (length=362) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYK
YHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRF
NDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYN
IPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAI
DQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLN
KRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLE
KRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKM
KFNVAMGIGVLD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1svl Chain B Residue 700 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1svl Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.
Resolution1.95 Å
Binding residue
(original residue number in PDB)
C302 C305 H313 H317
Binding residue
(residue number reindexed from 1)
C37 C40 H48 H52
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication

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Molecular Function

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Biological Process
External links
PDB RCSB:1svl, PDBe:1svl, PDBj:1svl
PDBsum1svl
PubMed15454080
UniProtP03070|LT_SV40 Large T antigen

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