Structure of PDB 1sox Chain B Binding Site BS01

Receptor Information
>1sox Chain B (length=458) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SYPEYTREEVGRHRSPEERVWVTHGTDVFDVTDFVELHPGGPDKILLAAG
GALEPFWALYAVHGEPHVLELLQQYKVGELSPDDAQDPFAGDPPRHPGLR
VNSQKPFNAEPPAELLAERFLTPNELFFTRNHLPVPAVEPSSYRLRVDGP
GGGTLSLSLAELRSRFPKHEVTATLQCAGNRRSEMSRVRPVKGLPWDIGA
ISTARWGGARLRDVLLHAGFPEELQGEWHVCFEGLDADPGGAPYGASIPY
GRALSPAADVLLAYEMNGTELPRDHGFPVRVVVPGVVGARSVKWLRRVAV
SPDESPSHWQQNDYKGFSPCVDWDTVDYRTAPAIQELPVQSAVTQPRPGA
AVPPGELTVKGYAWSGGGREVVRVDVSLDGGRTWKVARLMGDKAPPGRAW
AWALWELTVPVEAGTELEIVCKAVDSSYNVQPDSVAPIWNLRGVLSTAWH
RVRVSVQD
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1sox Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1sox Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		R138 R190 W204 Y322 R450
Binding residue
(residue number reindexed from 1)		R130 R182 W196 Y314 R442
Annotation score5
Enzymatic activity
Catalytic site (original residue number in PDB) H40 H65 R138 C185 D321 Y322
Catalytic site (residue number reindexed from 1) H38 H63 R130 C177 D313 Y314
Enzyme Commision number 1.8.3.1: sulfite oxidase.
Gene Ontology
Molecular Function
GO:0008482 sulfite oxidase activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0030151 molybdenum ion binding
GO:0043546 molybdopterin cofactor binding
GO:0046872 metal ion binding
Biological Process
GO:0006790 sulfur compound metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1sox, PDBe:1sox, PDBj:1sox
PDBsum1sox
PubMed9428520
UniProtP07850|SUOX_CHICK Sulfite oxidase (Gene Name=SUOX)

[Back to BioLiP]