Structure of PDB 1sf1 Chain B Binding Site BS01

Receptor Information
>1sf1 Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>1sf1 Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1sf1 Mechanism of insulin fibrillation: the structure of insulin under amyloidogenic conditions resembles a protein-folding intermediate
ResolutionN/A
Binding residue
(original residue number in PDB)
L6 C7 L11 L15 C19
Binding residue
(residue number reindexed from 1)
L6 C7 L11 L15 C19
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:1sf1, PDBe:1sf1, PDBj:1sf1
PDBsum1sf1
PubMed14988398
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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