Structure of PDB 1seb Chain B Binding Site BS01

Receptor Information
>1seb Chain B (length=192) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDTRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAV
TELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVT
VYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN
GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1seb Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		L11 F13 W61 Y78 H81 N82 V85
Binding residue
(residue number reindexed from 1)		L11 F13 W61 Y78 H81 N82 V85
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1seb, PDBe:1seb, PDBj:1seb
PDBsum1seb
PubMed8152483
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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