Structure of PDB 1rwe Chain B Binding Site BS01

Receptor Information
>1rwe Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>1rwe Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCHSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1rwe Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28
Binding residue
(residue number reindexed from 1)		Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 P28
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1rwe, PDBe:1rwe, PDBj:1rwe
PDBsum1rwe
PubMed15610006
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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