Structure of PDB 1rrv Chain B Binding Site BS01

Receptor Information
>1rrv Chain B (length=400) Species: 31958 (Amycolatopsis orientalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRVLLSVCGTRGDVEIGVALADRLKALGVQTRMCAPPAAEERLAEVGVPH
VPVGLPQHMMLQEGMPPPPPEEEQRLAAMTVEMQFDAVPGAAEGCAAVVA
VGDLAAATGVRSVAEKLGLPFFYSVPSPVYLASPHLPPAYDEPTTPGVTD
IRVLWEERAARFADRYGPTLNRRRAEIGLPPVEDVFGYGHGERPLLAADP
VLAPLQPDVDAVQTGAWLLSDERPLPPELEAFLAAGSPPVHIGFGSSSGR
GIADAAKVAVEAIRAQGRRVILSRGWTELVLPDDRDDCFAIDEVNFQALF
RRVAAVIHHGSAGTEHVATRAGVPQLVIPRNTDQPYFAGRVAALGIGVAH
DGPTPTFESLSAALTTVLAPETRARAEAVAGMVLTDGAAAAADLVLAAVG
Ligand information
Receptor-Ligand Complex Structure
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PDB1rrv Crystal Structure of Vancosaminyltransferase Gtfd from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands
Resolution2.0 Å
Binding residue
(original residue number in PDB)		C8 G9 T10 M60 L61 Q62 M65 P67 L76 T80 D141 P143 Y166 N331
Binding residue
(residue number reindexed from 1)		C8 G9 T10 M60 L61 Q62 M65 P67 L76 T80 D141 P143 Y166 N331
Enzymatic activity
Enzyme Commision number 2.4.1.322: devancosaminyl-vancomycin vancosaminetransferase.
Gene Ontology
Molecular Function
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0017000 antibiotic biosynthetic process
GO:0030259 lipid glycosylation
GO:0033072 vancomycin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1rrv, PDBe:1rrv, PDBj:1rrv
PDBsum1rrv
PubMed15122882
UniProtQ9AFC7|GTFD_AMYOR Devancosaminyl-vancomycin vancosaminetransferase (Gene Name=gtfD)

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