Structure of PDB 1rn1 Chain B Binding Site BS01

Receptor Information

>1rn1 Chain B (length=103) Species: 5062 (Aspergillus oryzae)

CDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVGSNSYPHKYNNYEGFDFS
VSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTGASGNNFV
ECT

Ligand information

• Ligand ID: SO4
• InChI: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
• InChIKey: QAOWNCQODCNURD-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: [O-]S(=O)(=O)[O-]
  CACTVS 3.341: [O-][S]([O-])(=O)=O
  ACDLabs 10.04: [O-]S([O-])(=O)=O
• Formula: O4 S
• Name: SULFATE ION
• DrugBank: DB14546
• PDB chain: 1rn1 Chain B Residue 106

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1rn1 Three-dimensional structure of Gln25-ribonuclease T1 at 1.84-A resolution: structural variations at the base recognition and catalytic sites.
• Resolution: 1.84 Å
• Binding residue (original residue number in PDB): Y38 E58 R77 H92 F100
• Binding residue (residue number reindexed from 1): Y37 E57 R76 H91 F99
• Annotation score: 3

Enzymatic activity

• Catalytic site (original residue number in PDB): Y38 H40 E58 D76 R77 T91 H92 F100
• Catalytic site (residue number reindexed from 1): Y37 H39 E57 D75 R76 T90 H91 F99
• Enzyme Commision number: 4.6.1.24: ribonuclease T1.

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0004519 endonuclease activity
• GO:0004521 RNA endonuclease activity
• GO:0004540 RNA nuclease activity
• GO:0016829 lyase activity
• GO:0046589 ribonuclease T1 activity

Biological Process

• GO:0008150 biological_process

Cellular Component

• GO:0001411 hyphal tip
• GO:0030428 cell septum

External links

• PDB: RCSB:1rn1, PDBe:1rn1, PDBj:1rn1
• PDBsum: 1rn1
• PubMed: 1554699
• UniProt: P00651|RNT1_ASPOR Guanyl-specific ribonuclease T1 (Gene Name=rntA)