Structure of PDB 1qwr Chain B Binding Site BS01

Receptor Information

>1qwr Chain B (length=314) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QSPIFLTPVFKEKIWGGTALRDRFGYSIPSESTGECWAISAHPKGPSTVA
NGPYKGKTLIELWEEHREVFGGVEGDRFPLLTKLLDVKEDTSIKVHPDDY
YAGENEEGELGKTECWYIIDCKENAEIIYGHTARSKTELVTMINSGDWEG
LLRRIKIKPGDFYYVPSGTLHALCKGALVLETQQNSDATYRVYDYDRLDS
NGSPRELHFAKAVNAATVPHVDGYIDESTESRKGITIKTFVQGEYFSVYK
WDINGEAEMAQDESFLICSVIEGSGLLKYEDKTCPLKKGDHFILPAQMPD
FTIKGTCTLIVSHI

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

1qwr Chain B Residue 605 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1qwr Crystal structure analysis of the mannose 6-phosphate isomerase from Bacillus subtilis
Resolution	1.8 Å
Binding residue (original residue number in PDB)	H98 E116 H173
Binding residue (residue number reindexed from 1)	H96 E114 H171
Annotation score	1

Enzymatic activity

Enzyme Commision number

5.3.1.8: mannose-6-phosphate isomerase.

Gene Ontology

	Molecular Function
GO:0004476	mannose-6-phosphate isomerase activity
GO:0008270	zinc ion binding
GO:0016853	isomerase activity
GO:0046872	metal ion binding

	Biological Process
GO:0005975	carbohydrate metabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:1qwr, PDBe:1qwr, PDBj:1qwr
PDBsum	1qwr
PubMed
UniProt	P39841\|MANA3_BACSU Putative mannose-6-phosphate isomerase YvyI (Gene Name=yvyI)

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