Structure of PDB 1qs8 Chain B Binding Site BS01

Receptor Information
>1qs8 Chain B (length=328) Species: 5855 (Plasmodium vivax) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSENDVIELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNS
SGCSIKNLYDSSKSKSYEKDGTKVDITYGSGTVKGFFSKDLVTLGHLSMP
YKFIEVIDTDDLEPIYSSVEFDGILGLGWKDLSIGSIDPIVVELKNQNKI
DNALFTFYLPVHDVHAGYLTIGGIEEKFYEGNITYEKLNHDLYWQIDLDV
HFGKQTMEKANVIVDSGTTTITAPSEFLNKFFANLNVIKVPFLPFYVTTC
DNKEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITMLPVDIDSNTF
ILGDPFMRKYFTVFDYDKESVGFAIAKN
Ligand information
>1qs8 Chain D (length=6) Species: 285516 (Streptomyces argenteolus subsp. toyonakensis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
VVVLAL
Receptor-Ligand Complex Structure
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PDB1qs8 Structural insights into the activation of P. vivax plasmepsin.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D34 G36 S37 T76 Y77 G78 S79 Y192 D214 G216 T217 T218
Binding residue
(residue number reindexed from 1)		D35 G37 S38 T77 Y78 G79 S80 Y193 D215 G217 T218 T219
Enzymatic activity
Catalytic site (original residue number in PDB) D34 S37 N39 W41 Y77 D214 T217
Catalytic site (residue number reindexed from 1) D35 S38 N40 W42 Y78 D215 T218
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1qs8, PDBe:1qs8, PDBj:1qs8
PDBsum1qs8
PubMed12767832
UniProtO60989

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