Structure of PDB 1qo0 Chain B Binding Site BS01

Receptor Information
>1qo0 Chain B (length=374) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPLIGLLFSETGVTADIERSQRYGALLAVEQLNREGGVGGRPIETLSQDP
GGDPDRYRLCAEDFIRNRGVRFLVGCYMSHTRKAVMPVVERADALLCYPT
PYEGFEYSPNIVYGGPAPNQNSAPLAAYLIRHYGERVVFIGSDYIYPRES
NHVMRHLYRQHGGTVLEEIYIPLYPSDDDLQRAVERIYQARADVVFSTVV
GTGTAELYRAIARRYGDGRRPPIASLTTSEAEVAKMESDVAEGQVVVAPY
FSSIDTPASRAFVQACHGFFPENATITAWAEAAYWQTLLLGRAAQAAGNW
RVEDVQRHLYDIDIDAPQGPVRVERQNNHSRLSSRIAEIDARGVFQVRWQ
SPEPIRPDPYVVVHNLDDWSASMG
Ligand information
Ligand IDBMD
InChIInChI=1S/C4H9NO/c1-2-3-4(5)6/h2-3H2,1H3,(H2,5,6)
InChIKeyDNSISZSEWVHGLH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(N)CCC
OpenEye OEToolkits 1.5.0CCCC(=O)N
CACTVS 3.341CCCC(N)=O
FormulaC4 H9 N O
NameBUTYRAMIDE
ChEMBLCHEMBL1231396
DrugBankDB02121
ZINCZINC000001586734
PDB chain1qo0 Chain B Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1qo0 Crystal Structure and Induction Mechanism of Amic-Amir: A Ligand-Regulated Transcription Antitermination Complex
Resolution2.25 Å
Binding residue
(original residue number in PDB)		Y83 M84 S85 P107 Y150 Y152
Binding residue
(residue number reindexed from 1)		Y77 M78 S79 P101 Y144 Y146
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016301 kinase activity
GO:0033218 amide binding
Biological Process
GO:0006865 amino acid transport
GO:0016310 phosphorylation
GO:0034251 regulation of amide catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1qo0, PDBe:1qo0, PDBj:1qo0
PDBsum1qo0
PubMed10508151
UniProtP27017|AMIC_PSEAE Aliphatic amidase expression-regulating protein (Gene Name=amiC)

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