Structure of PDB 1qf8 Chain B Binding Site BS01

Receptor Information
>1qf8 Chain B (length=163) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILD
LEPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVY
CENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGF
PHMLFMVHPEYRP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1qf8 Chain B Residue 216 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1qf8 Crystal structure of the human protein kinase CK2 regulatory subunit reveals its zinc finger-mediated dimerization.
Resolution1.74 Å
Binding residue
(original residue number in PDB)		C109 C114 C137 C140
Binding residue
(residue number reindexed from 1)		C96 C101 C124 C127
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11, 2.7.11.12, 2.7.11.13, 2.7.11.21, 2.7.11.22, 2.7.11.24, 2.7.11.25, 2.7.11.30 and 2.7.12.1.
Gene Ontology
Molecular Function
GO:0019887 protein kinase regulator activity
Cellular Component
GO:0005956 protein kinase CK2 complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1qf8, PDBe:1qf8, PDBj:1qf8
PDBsum1qf8
PubMed10357806
UniProtP67870|CSK2B_HUMAN Casein kinase II subunit beta (Gene Name=CSNK2B)

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