Structure of PDB 1q8y Chain B Binding Site BS01
Receptor Information
>1q8y Chain B (length=357) Species:
4932
(Saccharomyces cerevisiae) [
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PAFKGEPYKDARYILVRKLGFSTVWLAKDMVNNTHVAMKIVRGDKVYTEA
AEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVVMVFEV
LGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPE
NVLMEIVDSPENLIQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAP
WGCGADIWSTACLIFELITGDFLFEPDEGHSYTKDDDHIAQIIELLGELP
SYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEIS
DFLSPMLQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIP
GWFEEVR
Ligand information
Ligand ID
ADE
InChI
InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)
InChIKey
GFFGJBXGBJISGV-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
Nc1ncnc2[nH]cnc12
OpenEye OEToolkits 1.5.0
c1[nH]c2c(n1)c(ncn2)N
ACDLabs 10.04
n1c(c2ncnc2nc1)N
Formula
C5 H5 N5
Name
ADENINE
ChEMBL
CHEMBL226345
DrugBank
DB00173
ZINC
ZINC000000000882
PDB chain
1q8y Chain B Residue 900 [
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Receptor-Ligand Complex Structure
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PDB
1q8y
Nucleotide-Induced Conformational Changes in the Saccharomyces cerevisiae SR Protein Kinase, Sky1p, Revealed by X-Ray Crystallography
Resolution
2.05 Å
Binding residue
(original residue number in PDB)
A185 E247 V248 L249
Binding residue
(residue number reindexed from 1)
A37 E99 V100 L101
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
D294 K296 N299 D550 T567
Catalytic site (residue number reindexed from 1)
D146 K148 N151 D170 T187
Enzyme Commision number
2.7.11.1
: non-specific serine/threonine protein kinase.
Gene Ontology
Molecular Function
GO:0004672
protein kinase activity
GO:0005524
ATP binding
Biological Process
GO:0006468
protein phosphorylation
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Molecular Function
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Biological Process
External links
PDB
RCSB:1q8y
,
PDBe:1q8y
,
PDBj:1q8y
PDBsum
1q8y
PubMed
12911299
UniProt
Q03656
|SKY1_YEAST Serine/threonine-protein kinase SKY1 (Gene Name=SKY1)
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