Structure of PDB 1q4k Chain B Binding Site BS01
Receptor Information
>1q4k Chain B (length=224) Species:
9606
(Homo sapiens) [
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DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDK
YGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPN
SLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSA
IILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEY
GCCKELASRLRYARTMVDKLLSSR
Ligand information
>1q4k Chain E (length=6) [
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MQSTPL
Receptor-Ligand Complex Structure
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PDB
1q4k
The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
W414 D416 Y485 E488 H489 L490 L491 R516 F535 H538 K540
Binding residue
(residue number reindexed from 1)
W44 D46 Y115 E118 H119 L120 L121 R146 F165 H168 K170
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:1q4k
,
PDBe:1q4k
,
PDBj:1q4k
PDBsum
1q4k
PubMed
14592974
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
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