Structure of PDB 1pnv Chain B Binding Site BS01

Receptor Information
>1pnv Chain B (length=384) Species: 31958 (Amycolatopsis orientalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRVLITGCGSRGDTEPLVALAARLRELGADARMCLPPDYVERCAEVGVPM
VPVGRAVRAGAREPGELPPGAAEVVTEVVAEWFDKVPAAIEGCDAVVTTG
LLPAAVAVRSMAEKLGIPYRYTVLSPDHLPSEQSQAERDMYNQGADRLFG
DAVNSHRASIGLPPVEHLYDYGYTDQPWLAADPVLSPLRPTDLGTVQTGA
WILPDERPLSAELEAFLAAGSTPVYVGFGSSSRPATADAAKMAIKAVRAS
GRRIVLSRGWADLVLPDDGADCFVVGEVNLQELFGRVAAAIHHDSAGTTL
LAMRAGIPQIVVRRVAYHADRVAELGVGVAVDGPVPTIDSLSAALDTALA
PEIRARATTVADTIRADGTTVAAQLLFDAVSLEK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1pnv Structure of the Tdp-Epi-Vancosaminyltransferase Gtfa from the Chloroeremomycin Biosynthetic Pathway.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S10 D13 P69 G70 A72 L101 L102 P103 Y141 G144 L148 Y169
Binding residue
(residue number reindexed from 1)		S10 D13 P69 G70 A72 L101 L102 P103 Y141 G144 L148 Y169
Enzymatic activity
Enzyme Commision number 2.4.1.311: dTDP-epi-vancosaminyltransferase.
Gene Ontology
Molecular Function
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0017000 antibiotic biosynthetic process
GO:0030259 lipid glycosylation
GO:0033072 vancomycin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1pnv, PDBe:1pnv, PDBj:1pnv
PDBsum1pnv
PubMed12874381
UniProtP96558|GTFA_AMYOR dTDP-epi-vancosaminyltransferase (Gene Name=gtfA)

[Back to BioLiP]