Structure of PDB 1pau Chain B Binding Site BS01

Receptor Information
>1pau Chain B (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI
LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
Ligand information
Receptor-Ligand Complex Structure
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PDB1pau The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Y338 S339 W340 R341 N342 S343 S381A
Binding residue
(residue number reindexed from 1)		Y19 S20 W21 R22 N23 S24 S64
Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1pau, PDBe:1pau, PDBj:1pau
PDBsum1pau
PubMed8673606
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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