Structure of PDB 1p0k Chain B Binding Site BS01

Receptor Information
>1p0k Chain B (length=309) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ETGLDDITFVHVSLPDLALEQVDISTKIGELSSSSPIFINAMTGGGGKLT
YEINKSLARAASQAGIPLAVGSQMSALKDPSERLSYEIVRKENPNGLIFA
NLGSEATAAQAKEAVEMIGANALQIHLNVIQEIVMRSFSGALKRIEQICS
RVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGRQISFFNSWGISTAA
SLAEIRSEFPASTMIASGGLQDALDVAKAIALGASCTGMAGHFLKALTDS
GEEGLLEEIQLILEELKLIMTVLGARTIADLQKAPLVIKGETHHWLTERG
VNTSSYSVR
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain1p0k Chain B Residue 2400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1p0k Crystal Structure of the Type II Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase from Bacillus subtilis
Resolution1.9 Å
Binding residue
(original residue number in PDB)		G258 G281
Binding residue
(residue number reindexed from 1)		G218 G241
Annotation score1
Enzymatic activity
Enzyme Commision number 5.3.3.2: isopentenyl-diphosphate Delta-isomerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004452 isopentenyl-diphosphate delta-isomerase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0070402 NADPH binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1p0k, PDBe:1p0k, PDBj:1p0k
PDBsum1p0k
PubMed12798687
UniProtP50740|IDI2_BACSU Isopentenyl-diphosphate delta-isomerase (Gene Name=fni)

[Back to BioLiP]