Structure of PDB 1ol2 Chain B Binding Site BS01

Receptor Information
>1ol2 Chain B (length=258) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE
YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE
VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQP
ANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPE
SLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLL
NPPETLNL
Ligand information
Receptor-Ligand Complex Structure
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PDB1ol2 Insights Into Cyclin Groove Recognition. Complex Crystal Structures and Inhibitor Design Through Ligand Exchange
Resolution2.6 Å
Binding residue
(original residue number in PDB)		M210 W217 E220 R250 Q254 I281 T282 T285
Binding residue
(residue number reindexed from 1)		M36 W43 E46 R76 Q80 I107 T108 T111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:1ol2, PDBe:1ol2, PDBj:1ol2
PDBsum1ol2
PubMed14656438
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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