Structure of PDB 1o7l Chain B Binding Site BS01

Receptor Information
>1o7l Chain B (length=256) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGISYKSAWD
AINEMNQLSEHILVERATGAVLTRYGQRLIQLYDLLAQIQQKAFDVLSDD
DALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKT
RLKVAITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGI
ISHIERGAEQCEVLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSV
IIATLC
Ligand information
Ligand IDMOO
InChIInChI=1S/Mo.4O/q;;;2*-1
InChIKeyMEFBJEMVZONFCJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-][Mo](=O)(=O)[O-]
ACDLabs 10.04
CACTVS 3.341		[O-][Mo]([O-])(=O)=O
FormulaMo O4
NameMOLYBDATE ION;
MOLYBDATE
ChEMBL
DrugBankDB15878
ZINC
PDB chain1o7l Chain A Residue 1263 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1o7l Crystal Structure of Activated Mode Reveals Conformational Changes Involving Both Oxyanion and DNA-Binding Domains
Resolution2.75 Å
Binding residue
(original residue number in PDB)		I162 T163 S166
Binding residue
(residue number reindexed from 1)		I156 T157 S160
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0030151 molybdenum ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0015689 molybdate ion transport
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
GO:2000143 negative regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0032991 protein-containing complex
GO:1990198 ModE complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1o7l, PDBe:1o7l, PDBj:1o7l
PDBsum1o7l
PubMed12581638
UniProtP0A9G8|MODE_ECOLI DNA-binding transcriptional dual regulator ModE (Gene Name=modE)

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