Structure of PDB 1np6 Chain B Binding Site BS01

Receptor Information
>1np6 Chain B (length=169) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHTHHDMDVDKPGK
DSYELRKAGAAQTIVASQQRWALMTETPDEEELDLQFLASRMDTSKLDLI
LVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLD
INDVEGLADFVVEWMQKQN
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1np6 Chain B Residue 205 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1np6 Insight into the role of Escherichia coli MobB in Molybdenum cofactor biosynthesis based on the high resolution crystal structure
Resolution1.9 Å
Binding residue
(original residue number in PDB)		G17 G19 K20 T21
Binding residue
(residue number reindexed from 1)		G12 G14 K15 T16
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006777 Mo-molybdopterin cofactor biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1np6, PDBe:1np6, PDBj:1np6
PDBsum1np6
PubMed12682065
UniProtP32125|MOBB_ECOLI Molybdopterin-guanine dinucleotide biosynthesis adapter protein (Gene Name=mobB)

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