Structure of PDB 1n86 Chain B Binding Site BS01

Receptor Information
>1n86 Chain B (length=307) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVS
CNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWT
VIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKIS
QLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAG
NALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGG
GWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKM
SMKIRPF
Ligand information
Receptor-Ligand Complex Structure
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PDB1n86 The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		L360 N364 M367 W385 E397 D398 R406 C407 H408 D432
Binding residue
(residue number reindexed from 1)		L210 N214 M217 W235 E247 D248 R256 C257 H258 D282
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1n86, PDBe:1n86, PDBj:1n86
PDBsum1n86
PubMed12501189
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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