Structure of PDB 1mmy Chain B Binding Site BS01

Receptor Information
>1mmy Chain B (length=346) Species: 1358 (Lactococcus lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIKIRDFGLGSDLISLTNKAGVTISFTNLGARIVDWQKDGKHLILGFDSA
KEYLEKDAYPGATVGPTAGRIKDGLVKISGKDYILNQNEGPQTLHGGEES
IHTKLWTYEVTDLGAEVQVKFSLVSNDGTNGYPGKIEMSVTHSFDDDNKW
KIHYEAISDKDTVFNPTGHVYFNLNGDASESVENHGLRLAASRFVPLKDQ
TEIVRGDIVDIKNTDLDFRQEKQLSNAFNSNMEQVQLVKGIDHPFLLDQL
GLDKEQARLTLDDTSISVFTDQPSIVIFTANFGDLGTLYHEKKQVHHGGI
TFECQVSPGSEQIPELGDISLKAGEKYQATTIYSLHTKLEHHHHHH
Ligand information
Ligand IDG6D
InChIInChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3-,4+,5-,6+/m1/s1
InChIKeySHZGCJCMOBCMKK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01C1(C(O)C(O)C(O)C(O1)C)O
OpenEye OEToolkits 1.7.6CC1C(C(C(C(O1)O)O)O)O
OpenEye OEToolkits 1.7.6C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O
CACTVS 3.385C[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.385C[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
FormulaC6 H12 O5
Namealpha-D-quinovopyranose;
alpha-D-quinovose;
6-deoxy-alpha-D-glucopyranose;
D-quinovose;
quinovose;
6-DEOXY-ALPHA-D-GLUCOSE
ChEMBL
DrugBankDB03773
ZINCZINC000002042980
PDB chain1mmy Chain B Residue 348 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1mmy Structural and kinetic studies of sugar binding to galactose mutarotase from Lactococcus lactis.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		R71 H96 H170 D243 F279 E304
Binding residue
(residue number reindexed from 1)		R70 H95 H169 D242 F278 E303
Annotation score2
Enzymatic activity
Catalytic site (original residue number in PDB) H96 H170 E304
Catalytic site (residue number reindexed from 1) H95 H169 E303
Enzyme Commision number 5.1.3.3: aldose 1-epimerase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004034 aldose 1-epimerase activity
GO:0016853 isomerase activity
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
GO:0006012 galactose metabolic process
GO:0019318 hexose metabolic process
GO:0033499 galactose catabolic process via UDP-galactose
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1mmy, PDBe:1mmy, PDBj:1mmy
PDBsum1mmy
PubMed12218067
UniProtQ9ZB17

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