Structure of PDB 1lm4 Chain B Binding Site BS01

Receptor Information
>1lm4 Chain B (length=184) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEI
AKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHS
VQEAYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPA
IVFQHEIDHLNGVMFYDHIDKNHPLQPHTDAVEV
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1lm4 Chain B Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1lm4 Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
Resolution1.45 Å
Binding residue
(original residue number in PDB)		Q65 C111 H154 H158
Binding residue
(residue number reindexed from 1)		Q66 C112 H155 H159
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G60 Q65 C111 L112 H154 E155 H158
Catalytic site (residue number reindexed from 1) G61 Q66 C112 L113 H155 E156 H159
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

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Molecular Function
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Biological Process
External links
PDB RCSB:1lm4, PDBe:1lm4, PDBj:1lm4
PDBsum1lm4
PubMed12823970
UniProtP68826|DEF_STAAU Peptide deformylase (Gene Name=def)

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