Structure of PDB 1lcv Chain B Binding Site BS01

Receptor Information
>1lcv Chain B (length=118) Species: 1895 (Streptomyces avidinii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPA
TDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTT
EANAWKSTLVGHDTFTKV
Ligand information
Ligand IDSNR
InChIInChI=1S/C9H14N2O3S/c12-7(13)3-1-2-6-8-5(4-15-6)10-9(14)11-8/h5-6,8H,1-4H2,(H,12,13)(H2,10,11,14)/t5-,6-,8-/m0/s1
InChIKeyAINAXQHKYSZESH-HAFWLYHUSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC(=O)CCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
OpenEye OEToolkits 1.5.0C1[C@H]2[C@@H]([C@@H](S1)CCCC(=O)O)NC(=O)N2
OpenEye OEToolkits 1.5.0C1C2C(C(S1)CCCC(=O)O)NC(=O)N2
CACTVS 3.341OC(=O)CCC[CH]1SC[CH]2NC(=O)N[CH]12
ACDLabs 10.04O=C1NC2C(SCC2N1)CCCC(=O)O
FormulaC9 H14 N2 O3 S
NameNORBIOTIN;
4-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-4-YL)-BUTYRIC ACID
ChEMBL
DrugBankDB02674
ZINC
PDB chain1lcv Chain B Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1lcv Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
Resolution2.3 Å
Binding residue
(original residue number in PDB)		N223 S227 Y243 S245 W279 T290 W308 D328
Binding residue
(residue number reindexed from 1)		N8 S12 Y28 S30 W64 T75 W93 D113
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:1lcv, PDBe:1lcv, PDBj:1lcv
PDBsum1lcv
PubMed12055191
UniProtP22629|SAV_STRAV Streptavidin

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