Structure of PDB 1l7o Chain B Binding Site BS01

Receptor Information
>1l7o Chain B (length=208) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKKLILFNFDSTLVNNETIDEIAREAGVEEEVKKITKEAMEGKLNFEQSL
RKRVSLLKDLPIEKVEKAIKRITPTEGAEETIKELKNRGYVVAVVSGGFD
IAVNKIKEKLGLDYAFANRLIVKDGKLTGDVEGEVLKENAKGEILEKIAK
IEGINLEDTVAVGDGANDISMFKKAGLKIAFCAKPILKEKADICIEKRDL
REILKYIK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1l7o Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1l7o Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		C697 E699
Binding residue
(residue number reindexed from 1)		C194 E196
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) N511 F512 D513 G600 K644 D671
Catalytic site (residue number reindexed from 1) N8 F9 D10 G97 K141 D168
Enzyme Commision number 3.1.3.3: phosphoserine phosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0036424 L-phosphoserine phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006564 L-serine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1l7o, PDBe:1l7o, PDBj:1l7o
PDBsum1l7o
PubMed12051918
UniProtQ58989|SERB_METJA Phosphoserine phosphatase (Gene Name=MJ1594)

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