Structure of PDB 1l2i Chain B Binding Site BS01
Receptor Information
>1l2i Chain B (length=232) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAH
Ligand information
>1l2i Chain D (length=10) Species:
10090
(Mus musculus) [
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KHKILHRLLQ
Receptor-Ligand Complex Structure
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PDB
1l2i
Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 V72 D223 L224 E227
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1l2i
,
PDBe:1l2i
,
PDBj:1l2i
PDBsum
1l2i
PubMed
11953755
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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