Structure of PDB 1kmf Chain B Binding Site BS01

Receptor Information
>1kmf Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSDLVEALYLVCGERGFFYTKPT
Ligand information
>1kmf Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1kmf Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.
ResolutionN/A
Binding residue
(original residue number in PDB)
F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 Y26 T27 P29
Binding residue
(residue number reindexed from 1)
F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 Y26 T27 P29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:1kmf, PDBe:1kmf, PDBj:1kmf
PDBsum1kmf
PubMed11866509
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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