Structure of PDB 1kjh Chain B Binding Site BS01
Receptor Information
>1kjh Chain B (length=99) Species:
11676
(Human immunodeficiency virus 1) [
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PQITLWKRPLVTIRIGGQLKEALLNTGADDTVLEEMNLPGKWKPKMIGGI
GGFIKVRQYDQIPVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Ligand information
>1kjh Chain P (length=10) Species:
11678
(Human immunodeficiency virus type 1 BH10) [
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IRKILFLDGI
Receptor-Ligand Complex Structure
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PDB
1kjh
Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
R8 G27 A28 D29 D30 G48 G49 P81 V82 I84
Binding residue
(residue number reindexed from 1)
R8 G27 A28 D29 D30 G48 G49 P81 V82 I84
Enzymatic activity
Catalytic site (original residue number in PDB)
N25 T26 G27
Catalytic site (residue number reindexed from 1)
N25 T26 G27
Enzyme Commision number
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2
: exoribonuclease H.
3.1.26.13
: retroviral ribonuclease H.
3.4.23.16
: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0004190
aspartic-type endopeptidase activity
Biological Process
GO:0006508
proteolysis
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Molecular Function
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Biological Process
External links
PDB
RCSB:1kjh
,
PDBe:1kjh
,
PDBj:1kjh
PDBsum
1kjh
PubMed
12005435
UniProt
P03369
|POL_HV1A2 Gag-Pol polyprotein (Gene Name=gag-pol)
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