Structure of PDB 1kg0 Chain B Binding Site BS01

Receptor Information

>1kg0 Chain B (length=188) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TRPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTE
LGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVY
PSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGD
WTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA

Ligand information

>1kg0 Chain D (length=13) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PKYVKQNTLKLAT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1kg0 Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1.
Resolution	2.65 Å
Binding residue (original residue number in PDB)	L11 F13 Y47 P56 D57 Y60 W61 Q70 R71 Y78 H81 N82 V85
Binding residue (residue number reindexed from 1)	L9 F11 Y45 P54 D55 Y58 W59 Q68 R69 Y76 H79 N80 V83

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006955	immune response
GO:0019882	antigen processing and presentation

	Cellular Component
GO:0016020	membrane
GO:0042613	MHC class II protein complex

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Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:1kg0, PDBe:1kg0, PDBj:1kg0
PDBsum	1kg0
PubMed	11864610
UniProt	P01911\|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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