Structure of PDB 1k6o Chain B Binding Site BS01

Receptor Information
>1k6o Chain B (length=85) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLL
VASETGHVYTFATRKLQPMITSETGKALIQTCLNS
Ligand information
Receptor-Ligand Complex Structure
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PDB1k6o Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.
Resolution3.19 Å
Binding residue
(original residue number in PDB)		K138 K139 T140 G142 R143 K145 K163 K165 K171 Y195
Binding residue
(residue number reindexed from 1)		K2 K3 T4 G6 R7 K9 K27 K29 K35 Y59
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:1k6o, PDBe:1k6o, PDBj:1k6o
PDBsum1k6o
PubMed11846562
UniProtP11831|SRF_HUMAN Serum response factor (Gene Name=SRF)

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