Structure of PDB 1k3m Chain B Binding Site BS01

Receptor Information
>1k3m Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSDLVEALYLVCGERGFFYTKPT
Ligand information
>1k3m Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1k3m A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix.
ResolutionN/A
Binding residue
(original residue number in PDB)		F1 N3 H5 L6 C7 G8 L11 L15 V18 C19 G23 F24
Binding residue
(residue number reindexed from 1)		F1 N3 H5 L6 C7 G8 L11 L15 V18 C19 G23 F24
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1k3m, PDBe:1k3m, PDBj:1k3m
PDBsum1k3m
PubMed11742127
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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