Structure of PDB 1jpp Chain B Binding Site BS01

Receptor Information
>1jpp Chain B (length=502) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIV
RTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVD
SVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTD
CLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSV
CSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGME
GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVR
TVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLH
PPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQQQFV
EGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQ
RVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFR
MS
Ligand information
Receptor-Ligand Complex Structure
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PDB1jpp Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
K345 W383 R386 D390 N426 N430 H470
Binding residue
(residue number reindexed from 1)
K196 W234 R237 D241 N277 N281 H321
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

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Molecular Function

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Biological Process
External links
PDB RCSB:1jpp, PDBe:1jpp, PDBj:1jpp
PDBsum1jpp
PubMed11707392
UniProtQ02248|CTNB1_MOUSE Catenin beta-1 (Gene Name=Ctnnb1)

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