Structure of PDB 1jm4 Chain B Binding Site BS01

Receptor Information
>1jm4 Chain B (length=118) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI
RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCAN
ILEKFFFSKIKEAGLIDK
Ligand information
>1jm4 Chain A (length=11) Species: 11686 (Human immunodeficiency virus type 1 (BRU ISOLATE)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SYGRKKRRQRC
Receptor-Ligand Complex Structure
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PDB1jm4 Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain
ResolutionN/A
Binding residue
(original residue number in PDB)		V752 K753 E756 P758 G759 Y760 Y802
Binding residue
(residue number reindexed from 1)		V38 K39 E42 P44 G45 Y46 Y88
Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
2.3.1.57: diamine N-acetyltransferase.
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1jm4, PDBe:1jm4, PDBj:1jm4
PDBsum1jm4
PubMed11931765
UniProtQ92831|KAT2B_HUMAN Histone acetyltransferase KAT2B (Gene Name=KAT2B)

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