Structure of PDB 1jco Chain B Binding Site BS01

Receptor Information
>1jco Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYPTKT
Ligand information
>1jco Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1jco Flexibility and bioactivity of insulin: an NMR investigation of the solution structure and folding of an unusually flexible human insulin mutant with increased biological activity.
ResolutionN/A
Binding residue
(original residue number in PDB)
N3 Q4 H5 C7 L11 L15 V18 C19 G23 F24
Binding residue
(residue number reindexed from 1)
N3 Q4 H5 C7 L11 L15 V18 C19 G23 F24
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:1jco, PDBe:1jco, PDBj:1jco
PDBsum1jco
PubMed11524020
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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