Structure of PDB 1iza Chain B Binding Site BS01

Receptor Information

>1iza Chain B (length=30) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

FVNQHLCGSHLVQALYLVCGERGFFYTPKT

Ligand information

>1iza Chain A (length=21) Species: 9823 (Sus scrofa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

GIVEQCCTSICSLYQLENYCN

Receptor-Ligand Complex Structure

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PDB	1iza Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	C7 L15 V18 C19 R22 F25 Y26
Binding residue (residue number reindexed from 1)	C7 L15 V18 C19 R22 F25 Y26

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005179	hormone activity

	Cellular Component
GO:0005576	extracellular region

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1iza, PDBe:1iza, PDBj:1iza
PDBsum	1iza
PubMed	1361949
UniProt	P01315\|INS_PIG Insulin (Gene Name=INS)

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